Dazl is a target RNA suppressed by mammalian NANOS2 in sexually differentiating male germ cells
The Nanos family protein, NANOS2, is required for sexual differentiation of male germ cells in mice, however, the molecular RNA targets are unknown. Here, Kato et al. identify Dazl, a germ cell-specific gene, as being a target of NANOS, with stabilized DazlmRNA causing abnormal resumption of the cel...
Main Authors: | , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2016-04-01
|
Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/ncomms11272 |