Protamine Sulfate Neutralization Profile of Various Dosages of Bovine, Ovine and Porcine UFHs and Their Depolymerized Derivatives in Non-Human Primates

Introduction: Currently used unfractionated heparins (UFHs) and low molecular weight heparins (LMWHs) are derived from porcine intestinal mucosa. However, heparins have also been manufactured from tissues of other mammalian species such as cow (Bovine) and sheep (Ovine). Protamine sulphate (PS) is a...

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Bibliographic Details
Main Authors: Ahmed Kouta MS, MBA, Walter Jeske PhD, Lee Cera DVM, PhD, Azarfrooz Farshid DVM, Richard Duff BS, CVT (AVMA), Debra Hoppensteadt PhD, Jawed Fareed PhD
Format: Article
Language:English
Published: SAGE Publishing 2021-04-01
Series:Clinical and Applied Thrombosis/Hemostasis
Online Access:https://doi.org/10.1177/10760296211005544