Regulation of Parietal Cell Homeostasis by Bone Morphogenetic Protein Signaling

Regulation of Parietal Cell Homeostasis by Bone Morphogenetic Protein Signaling

Background and Aims: Loss of bone morphogenetic protein (BMP) signaling in the stomach, achieved by transgenic expression of the BMP inhibitor noggin (H+/K+-Nog mice), causes parietal cell (PC) loss, spasmolytic polypeptide-expressing metaplasia, a marker of preneoplasia, and activation of cell prol...

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Bibliographic Details
Main Authors: Hidehiko Takabayashi, Tuo Ji, Lei Peng, Xuan Li, Masahiko Shinohara, Maria Mao, Kathryn A. Eaton, Yatrik M. Shah, Andrea Todisco
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:Gastro Hep Advances
Subjects:
Dysplasia
Differentiation
Metaplasia
RNA-Seq
Online Access:http://www.sciencedirect.com/science/article/pii/S2772572322001686

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http://www.sciencedirect.com/science/article/pii/S2772572322001686

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