Single-cell transcriptomics identifies the common perturbations of monocyte/macrophage lineage cells in inflammaging of bone marrow

Background: Bone marrow inflammaging is a low-grade chronic inflammation that induces bone marrow aging. Multiple age-related and inflammatory diseases involve bone marrow inflammaging. Whether common pathological pathways exist in bone marrow inflammaging remains unclear. Methods: We collected bone...

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Bibliographic Details
Main Authors: Peng Liao, Sihan Tong, Lin Du, Jiong Mei, Bingqi Wang, Yafei Lu, Meng Yao, Changqing Zhang, Delin Liu, Zhigang Zhong, Fang Ye, Junjie Gao
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Journal of Orthopaedic Translation
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2214031X24001293