Virtual brain simulations reveal network-specific parameters in neurodegenerative dementias

Virtual brain simulations reveal network-specific parameters in neurodegenerative dementias

IntroductionNeural circuit alterations lay at the core of brain physiopathology, and yet are hard to unveil in living subjects. The Virtual Brain (TVB) modeling, by exploiting structural and functional magnetic resonance imaging (MRI), yields mesoscopic parameters of connectivity and synaptic transm...

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Bibliographic Details
Main Authors: Anita Monteverdi, Fulvia Palesi, Michael Schirner, Francesca Argentino, Mariateresa Merante, Alberto Redolfi, Francesca Conca, Laura Mazzocchi, Stefano F. Cappa, Matteo Cotta Ramusino, Alfredo Costa, Anna Pichiecchio, Lisa M. Farina, Viktor Jirsa, Petra Ritter, Claudia A. M. Gandini Wheeler-Kingshott, Egidio D’Angelo
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-07-01
Series:Frontiers in Aging Neuroscience
Subjects:
virtual brain modeling
brain dynamics
excitatory/inhibitory balance
Alzheimer’s disease
frontotemporal dementia
resting-state networks
Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2023.1204134/full

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https://www.frontiersin.org/articles/10.3389/fnagi.2023.1204134/full

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