Study on Absorption, Distribution and Excretion of a New Candidate Compound XYY-CP1106 against Alzheimer’s Disease in Rats by LC-MS/MS

Study on Absorption, Distribution and Excretion of a New Candidate Compound XYY-CP1106 against Alzheimer’s Disease in Rats by LC-MS/MS

XYY-CP1106, a candidate compound synthesized from a hybrid of hydroxypyridinone and coumarin, has been shown to be remarkably effective in treating Alzheimer’s disease. A simple, rapid and accurate high-performance liquid chromatography coupled with the triple quadrupole mass spectrometer (LC-MS/MS)...

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Bibliographic Details
Main Authors: Zili Guo, Bianbian Gao, Miaoliang Fan, Lisha Chen, Changjun Zhang, Xianrui Liang, Weike Su, Yuanyuan Xie
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Molecules
Subjects:
XYY-CP1106
Alzheimer’s disease
LC-MS/MS
pharmacokinetics
tissue distribution
excretion study
Online Access:https://www.mdpi.com/1420-3049/28/5/2377

Internet

https://www.mdpi.com/1420-3049/28/5/2377

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