Decreased chloride channel expression in the dorsolateral prefrontal cortex in schizophrenia.

Alterations in GABAergic neurotransmission are implicated in several psychiatric illnesses, including schizophrenia. The Na-K-Cl and K-Cl cotransporters regulate intracellular chloride levels. Abnormalities in cotransporter expression levels could shift the chloride electrochemical gradient and impa...

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Detalhes bibliográficos
Main Authors: Courtney R Sullivan, Adam J Funk, Dan Shan, Vahram Haroutunian, Robert E McCullumsmith
Formato: Artigo
Idioma:English
Publicado em: Public Library of Science (PLoS) 2015-01-01
Colecção:PLoS ONE
Acesso em linha:http://europepmc.org/articles/PMC4380350?pdf=render