Interleukin 7 requirement for survival of T-cell acute lymphoblastic leukemia and human thymocytes on bone marrow stroma

We explored the role of interleukin-7 (IL-7) in the bone marrow (BM) stroma-mediated survival of primary T-cell acute lymphoblastic leukemia (T-ALL) cells and normal thymocytes. We present evidence that IL-7 has a major role in the enhanced survival mediated by BM stroma both in T-ALL cells and thym...

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Bibliographic Details
Main Authors: Maria T. Scupoli, Omar Perbellini, Mauro Krampera, Fabrizio Vinante, Federica Cioffi, Giovanni Pizzolo
Format: Article
Language:English
Published: Ferrata Storti Foundation 2007-02-01
Series:Haematologica
Online Access:https://haematologica.org/article/view/4340