Interactions of the N- and C-Terminal SH3 Domains of <i>Drosophila</i> Drk with the Proline-Rich Peptides from Sos and Dos

Drk, a homologue of human GRB2 in <i>Drosophila</i>, receives signals from outside the cells through the interaction of its SH2 domain with the phospho-tyrosine residues in the intracellular regions of receptor tyrosine kinases (RTKs) such as Sevenless, and transduces the signals downstr...

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Bibliographic Details
Main Authors: Pooppadi Maxin Sayeesh, Mayumi Iguchi, Yusuke Suemoto, Jin Inoue, Kohsuke Inomata, Teppei Ikeya, Yutaka Ito
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/24/18/14135