Activation of Kir2.1 improves myocardial fibrosis by inhibiting Ca <sup>2+</sup> overload and the TGF-β1/Smad signaling pathway
The inwardly rectifying potassium channel Kir2.1 is closely associated with many cardiovascular diseases. However, the effect and mechanism of Kir2.1 in diabetic cardiomyopathy remain unclear. In vivo, we use STZ to establish the model, and ventricular structural changes, myocard...
Main Authors: | , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
China Science Publishing & Media Ltd.
2023-05-01
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Series: | Acta Biochimica et Biophysica Sinica |
Subjects: | |
Online Access: | https://www.sciengine.com/doi/10.3724/abbs.2023083 |