Plant flavonoid inhibition of SARS-CoV-2 main protease and viral replication

Plant flavonoid inhibition of SARS-CoV-2 main protease and viral replication

Summary: Plant-based flavonoids have been evaluated as inhibitors of β-coronavirus replication and as therapies for COVID-19 on the basis of their safety profile and widespread availability. The SARS-CoV-2 main protease (Mpro) has been implicated as a target for flavonoids in silico. Yet no comprehe...

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Bibliographic Details
Main Authors: Lin Lin, Da-Yuan Chen, Christina Scartelli, Huanzhang Xie, Glenn Merrill-Skoloff, Moua Yang, Lijun Sun, Mohsan Saeed, Robert Flaumenhaft
Format: Article
Language:English
Published: Elsevier 2023-09-01
Series:iScience
Subjects:
Pharmacology
Natural sciences
Chemistry
Natural product chemistry
Biological sciences
Biochemistry
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223016796

Internet

http://www.sciencedirect.com/science/article/pii/S2589004223016796

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