Somatic variant calling from single-cell DNA sequencing data

Somatic variant calling from single-cell DNA sequencing data

Single-cell sequencing has gained popularity in recent years. Despite its numerous applications, single-cell DNA sequencing data is highly error-prone due to technical biases arising from uneven sequencing coverage, allelic dropout, and amplification error. With these artifacts, the identification o...

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Bibliographic Details
Main Authors: Monica Valecha, David Posada
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:Computational and Structural Biotechnology Journal
Subjects:
Variant calling
Single-cell genomics
Allele dropout
Amplification error
Somatic variants
Online Access:http://www.sciencedirect.com/science/article/pii/S2001037022002264

Internet

http://www.sciencedirect.com/science/article/pii/S2001037022002264

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