2466 MicroRNA-451: A potential key player in the development of diabetic nephropathy in an insulin resistant mouse model

OBJECTIVES/SPECIFIC AIMS: MicroRNAs (miRNA) affect transcription of a number of genes involved in the development and progression of diabetic nephropathy (DN), and have become attractive therapeutic targets and biomarkers. Elevated renal gluconeogenesis, fibrosis, and albuminuria are early markers o...

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Bibliographic Details
Main Authors: Maurice B Fluitt, Lijun Li, Narayan Shivapurkar, Carolyn Ecelbarger
Format: Article
Language:English
Published: Cambridge University Press 2018-06-01
Series:Journal of Clinical and Translational Science
Online Access:https://www.cambridge.org/core/product/identifier/S205986611800095X/type/journal_article