Improved targeting of an anti‐TAG‐72 antibody drug conjugate for the treatment of ovarian cancer

Abstract Introduction Ovarian cancer has only a 17% 5‐year survival rate in patients diagnosed with late stage disease. Tumor‐associated glycoprotein‐72 (TAG72), expressed in 88% of all stages of ovarian cancer, is an excellent candidate for antibody‐targeted therapy, as it is not expressed in norma...

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Bibliographic Details
Main Authors: Megan Minnix, Lin Li, Paul Yazaki, Junie Chea, Erasmus Poku, David Colcher, John E. Shively
Format: Article
Language:English
Published: Wiley 2020-07-01
Series:Cancer Medicine
Subjects:
Online Access:https://doi.org/10.1002/cam4.3078