The Combination of Daptomycin with Fosfomycin is More Effective than Daptomycin Alone in Reducing Mortality of Vancomycin-Resistant Enterococcal Bloodstream Infections: A Retrospective, Comparative Cohort Study

The Combination of Daptomycin with Fosfomycin is More Effective than Daptomycin Alone in Reducing Mortality of Vancomycin-Resistant Enterococcal Bloodstream Infections: A Retrospective, Comparative Cohort Study

Abstract Introduction High-dose daptomycin-based combinations are recommended for vancomycin-resistant Enterococcus (VRE) bloodstream infection (BSI). Preclinical data have shown a synergistic effect of daptomycin/fosfomycin combinations against VRE. However, clinical studies comparing daptomycin mo...

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Bibliographic Details
Main Authors: Tai-Chung Tseng, Yu-Chung Chuang, Jia-Ling Yang, Chi-Ying Lin, Sung-Hsi Huang, Jann-Tay Wang, Yee-Chun Chen, Shan-Chwen Chang
Format: Article
Language:English
Published: Adis, Springer Healthcare 2023-01-01
Series:Infectious Diseases and Therapy
Subjects:
Combination
Daptomycin
Fosfomycin
Mortality
Vancomycin-resistant enterococci
Online Access:https://doi.org/10.1007/s40121-022-00754-1

Internet

https://doi.org/10.1007/s40121-022-00754-1

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