HIV-1–Host Interaction in Gut-Associated Lymphoid Tissue (GALT): Effects on Local Environment and Comorbidities

HIV-1–Host Interaction in Gut-Associated Lymphoid Tissue (GALT): Effects on Local Environment and Comorbidities

HIV-1 replication in the gastrointestinal (GI) tract causes severe CD4+ T-cell depletion and disruption of the protective epithelial barrier in the intestinal mucosa, causing microbial translocation, the main driver of inflammation and immune activation, even in people living with HIV (PLWH) taking...

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Bibliographic Details
Main Authors: Sonia Moretti, Ivan Schietroma, Giuseppe Sberna, Maria Teresa Maggiorella, Leonardo Sernicola, Stefania Farcomeni, Marta Giovanetti, Massimo Ciccozzi, Alessandra Borsetti
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:International Journal of Molecular Sciences
Subjects:
HIV-1 pathogenesis
GALT
gut dysbiosis
Th17
Treg
Tfh
Online Access:https://www.mdpi.com/1422-0067/24/15/12193

Internet

https://www.mdpi.com/1422-0067/24/15/12193

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