Imbalance of mitochondrial-nuclear cross talk in isocyanate mediated pulmonary endothelial cell dysfunction

Imbalance of mitochondrial-nuclear cross talk in isocyanate mediated pulmonary endothelial cell dysfunction

Mechanistic investigations coupled with epidemiology, case-control, cohort and observational studies have increasingly linked isocyanate exposure (both chronic and acute) with pulmonary morbidity and mortality. Though ascribed for impairment in endothelial cell function, molecular mechanisms of thes...

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Bibliographic Details
Main Authors: Hariom Panwar, Deepika Jain, Saba Khan, Neelam Pathak, Gorantla V. Raghuram, Arpit Bhargava, Smita Banerjee, Pradyumna K. Mishra
Format: Article
Language:English
Published: Elsevier 2013-01-01
Series:Redox Biology
Subjects:
Mitochondrial oxidative stress
Endothelial cell apoptosis
Pulmonary toxicity
Occupational health
Environmental medicine
Online Access:http://www.sciencedirect.com/science/article/pii/S221323171300030X

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http://www.sciencedirect.com/science/article/pii/S221323171300030X

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