Dual Role of Lysophosphatidic Acid Receptor 2 (LPA2) in Amyotrophic Lateral Sclerosis

Lysophosphatidic acid (LPA) is a pleiotropic extracellular lipid mediator with many physiological functions that signal through six known G protein-coupled receptors (LPA1–6). In the central nervous system (CNS), LPA mediates a wide range of effects including neural progenitor cell physiology, neuro...

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Bibliographic Details
Main Authors: Maria Puigdomenech-Poch, Anna Martínez-Muriana, Pol Andrés-Benito, Isidre Ferrer, Jerold Chun, Rubèn López-Vales
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fncel.2021.600872/full