Statistical methods and graphical displays of quality of life with survival outcomes in oncology clinical trials for supporting the estimand framework
Abstract Background Although there are discussions regarding standards of the analysis of patient-reported outcomes and quality of life (QOL) in oncology clinical trials, that of QOL with death events is not within their scope. For example, ignoring death can lead to bias in the QOL analysis for pat...
Main Authors: | Kentaro Sakamaki, Takuya Kawahara |
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Format: | Article |
Language: | English |
Published: |
BMC
2022-10-01
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Series: | BMC Medical Research Methodology |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12874-022-01735-1 |
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