Self-recognition drives the preferential accumulation of promiscuous CD4+ T-cells in aged mice
T-cell recognition of self and foreign peptide antigens presented in major histocompatibility complex molecules (pMHC) is essential for life-long immunity. How the ability of the CD4+ T-cell compartment to bind self- and foreign-pMHC changes over the lifespan remains a fundamental aspect of T-cell b...
| Автори: | , , |
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| Формат: | Стаття |
| Мова: | English |
| Опубліковано: |
eLife Sciences Publications Ltd
2015-07-01
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| Серія: | eLife |
| Предмети: | |
| Онлайн доступ: | https://elifesciences.org/articles/05949 |