Mitochondrial dysfunction mediated by thioredoxin-interacting protein: A crucial determinant in di(2-ethylhexyl) phthalate-induced liver failure

Mitochondrial dysfunction mediated by thioredoxin-interacting protein: A crucial determinant in di(2-ethylhexyl) phthalate-induced liver failure

Di(2-ethylhexyl) phthalate (DEHP) is a widely used plasticizer that can interfere with the endocrine system and cause liver damage. However, the molecular mechanism of DEHP-induced liver injury is unclear. This study aimed to investigate the effects of DEHP on liver function and its relationship wit...

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Bibliographic Details
Main Authors: Peng Xu, Yang-ni Su, Chen Ling, Jing Wang, Wang Zhang
Format: Article
Language:English
Published: Elsevier 2024-03-01
Series:Ecotoxicology and Environmental Safety
Subjects:
DEHP
TXNIP
NLRP3
Mitochondria
Oxidative stress
Liver failure
Online Access:http://www.sciencedirect.com/science/article/pii/S0147651324001787

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http://www.sciencedirect.com/science/article/pii/S0147651324001787

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