Role and Therapeutic Targeting of the HGF/MET Pathway in Glioblastoma

Glioblastoma (GBM) is a lethal brain tumor with dismal prognosis. Current therapeutic options, consisting of surgery, chemotherapy and radiation, have only served to marginally increase patient survival. Receptor tyrosine kinases (RTKs) are dysregulated in approximately 90% of GBM; attributed to thi...

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Bibliographic Details
Main Authors: Nichola Cruickshanks, Ying Zhang, Fang Yuan, Mary Pahuski, Myron Gibert, Roger Abounader
Format: Article
Language:English
Published: MDPI AG 2017-07-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/9/7/87