Presynaptic inhibition of dopamine neurons controls optimistic bias

Presynaptic inhibition of dopamine neurons controls optimistic bias

Regulation of reward signaling in the brain is critical for appropriate judgement of the environment and self. In Drosophila, the protocerebral anterior medial (PAM) cluster dopamine neurons mediate reward signals. Here, we show that localized inhibitory input to the presynaptic terminals of the PAM...

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Bibliographic Details
Main Authors: Nobuhiro Yamagata, Takahiro Ezaki, Takahiro Takahashi, Hongyang Wu, Hiromu Tanimoto
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-06-01
Series:eLife
Subjects:
reward
learning
memory
dopamine
subcellular calcium
GABA inhibition
Online Access:https://elifesciences.org/articles/64907

Internet

https://elifesciences.org/articles/64907

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