Prokaryotic Argonaute from Archaeoglobus fulgidus interacts with DNA as a homodimer

Abstract Argonaute (Ago) proteins are found in all three domains of life. The best-characterized group is eukaryotic Argonautes (eAgos), which are the core of RNA interference. The best understood prokaryotic Ago (pAgo) proteins are full-length pAgos. They are composed of four major structural/funct...

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Bibliographic Details
Main Authors: Edvardas Golovinas, Danielis Rutkauskas, Elena Manakova, Marija Jankunec, Arunas Silanskas, Giedrius Sasnauskas, Mindaugas Zaremba
Format: Article
Language:English
Published: Nature Portfolio 2021-02-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-83889-4