The myosin and RhoGAP MYO9B influences osteocyte dendrite growth and responses to mechanical stimuli

The myosin and RhoGAP MYO9B influences osteocyte dendrite growth and responses to mechanical stimuli

Introduction: Myosin IXB (MYO9B) is an unconventional myosin with RhoGAP activity and thus is a regulator of actin cytoskeletal organization. MYO9B was previously shown to be necessary for skeletal growth and health and to play a role in actin-based functions of both osteoblasts and osteoclasts. How...

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Bibliographic Details
Main Authors: Beth S. Lee, Cynthia Murray, Jie Liu, Minji Kim, Min Sik Hwang, Tina Yueh, Myrna Mansour, Sana Qamar, Gunjan Agarwal, Do-Gyoon Kim
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-08-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
bone
osteocytes
osteoblasts
mechanosignaling
RhoA
RhoGAP
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2023.1243303/full

Internet

https://www.frontiersin.org/articles/10.3389/fbioe.2023.1243303/full

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