Loss of Corneal Nerves and Corneal Haze in Patients with Fuchs’ Endothelial Corneal Dystrophy with the Transcription Factor 4 Gene Trinucleotide Repeat Expansion

Loss of Corneal Nerves and Corneal Haze in Patients with Fuchs’ Endothelial Corneal Dystrophy with the Transcription Factor 4 Gene Trinucleotide Repeat Expansion

Objective: Seventy percent of Fuchs’ endothelial corneal dystrophy (FECD) cases are caused by an intronic trinucleotide repeat expansion in the transcription factor 4 gene (TCF4). The objective of this study was to characterize the corneal subbasal nerve plexus and corneal haze in patients with FECD...

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Bibliographic Details
Main Authors: Matthew Gillings, MD, Andrew Mastro, MD, Xunzhi Zhang, Kelly Kiser, MD, Jane Gu, Chao Xing, PhD, Danielle M. Robertson, OD, PhD, W. Matthew Petroll, PhD, V. Vinod Mootha, MD
Format: Article
Language:English
Published: Elsevier 2023-03-01
Series:Ophthalmology Science
Subjects:
Confocal
Cornea
Fuchs’ endothelial corneal dystrophy
Imaging
Scheimpflug
Online Access:http://www.sciencedirect.com/science/article/pii/S2666914522001038

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http://www.sciencedirect.com/science/article/pii/S2666914522001038

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