Digital Microfluidics-Powered Real-Time Monitoring of Isothermal DNA Amplification of Cancer Biomarker

Digital Microfluidics-Powered Real-Time Monitoring of Isothermal DNA Amplification of Cancer Biomarker

We introduce a digital microfluidics (DMF) platform specifically designed to perform a loop-mediated isothermal amplification (LAMP) of DNA and applied it to a real-time amplification to monitor a cancer biomarker, <i>c-Myc</i> (associated to 40% of all human tumors), using fluorescence...

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Bibliographic Details
Main Authors: Beatriz Jorge Coelho, Bruno Veigas, Luís Bettencourt, Hugo Águas, Elvira Fortunato, Rodrigo Martins, Pedro V. Baptista, Rui Igreja
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Biosensors
Subjects:
digital microfluidics
loop-mediated isothermal amplification
real-time nucleic acid amplification monitoring
fluorescence detection
cancer biomarker
Online Access:https://www.mdpi.com/2079-6374/12/4/201

Internet

https://www.mdpi.com/2079-6374/12/4/201

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