Digital Microfluidics-Powered Real-Time Monitoring of Isothermal DNA Amplification of Cancer Biomarker

Digital Microfluidics-Powered Real-Time Monitoring of Isothermal DNA Amplification of Cancer Biomarker

We introduce a digital microfluidics (DMF) platform specifically designed to perform a loop-mediated isothermal amplification (LAMP) of DNA and applied it to a real-time amplification to monitor a cancer biomarker, <i>c-Myc</i> (associated to 40% of all human tumors), using fluorescence...

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Bibliographic Details
Main Authors:	Beatriz Jorge Coelho, Bruno Veigas, Luís Bettencourt, Hugo Águas, Elvira Fortunato, Rodrigo Martins, Pedro V. Baptista, Rui Igreja
Format:	Article
Language:	English
Published:	MDPI AG 2022-03-01
Series:	Biosensors
Subjects:	digital microfluidics loop-mediated isothermal amplification real-time nucleic acid amplification monitoring fluorescence detection cancer biomarker
Online Access:	https://www.mdpi.com/2079-6374/12/4/201

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