Exploring the Involvement of the Amyloid Precursor Protein A673T Mutation against Amyloid Pathology and Alzheimer’s Disease in Relation to Therapeutic Editing Tools

Exploring the Involvement of the Amyloid Precursor Protein A673T Mutation against Amyloid Pathology and Alzheimer’s Disease in Relation to Therapeutic Editing Tools

Alzheimer’s disease (AD) is biologically defined as a complex neurodegenerative condition with a multilayered nature that leads to a progressive decline in cognitive function and irreversible neuronal loss. It is one of the primary diseases among elderly individuals. With an increasing incidence and...

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Bibliographic Details
Main Authors: Gabriela Dumitrita Stanciu, Daniela Carmen Ababei, Razvan Nicolae Rusu, Veronica Bild, Bogdan-Ionel Tamba
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Pharmaceutics
Subjects:
Alzheimer’s disease
amyloid precursor protein
A673T mutation
therapeutic editing tools
CRISPR/Cas9
cognitive decline
Online Access:https://www.mdpi.com/1999-4923/14/6/1270

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https://www.mdpi.com/1999-4923/14/6/1270

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