Alterations of monocyte NF-κB p65/RelA signaling in a cohort of older medical patients, age-matched controls, and healthy young adults

Alterations of monocyte NF-κB p65/RelA signaling in a cohort of older medical patients, age-matched controls, and healthy young adults

Abstract Background Altered monocyte NF-κB signaling is a possible cause of inflammaging and driver of aging, however, evidence from human aging studies is sparse. We assessed monocyte NF-κB signaling across different aging trajectories by comparing healthy older adults to older adults with a recent...

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Bibliographic Details
Main Authors: Juliette Tavenier, Line Jee Hartmann Rasmussen, Morten Baltzer Houlind, Aino Leegaard Andersen, Inge Panum, Ove Andersen, Janne Petersen, Anne Langkilde, Jan O. Nehlin
Format: Article
Language:English
Published: BMC 2020-09-01
Series:Immunity & Ageing
Subjects:
Aging
Monocyte
NF-κB
Immunosenescence
Chronic inflammation
Inflammaging
Online Access:http://link.springer.com/article/10.1186/s12979-020-00197-7

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http://link.springer.com/article/10.1186/s12979-020-00197-7

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