Blood immunophenotyping of multiple sclerosis patients at diagnosis identifies a classical monocyte subset associated to disease evolution

Blood immunophenotyping of multiple sclerosis patients at diagnosis identifies a classical monocyte subset associated to disease evolution

IntroductionMyeloid cells trafficking from the periphery to the central nervous system are key players in multiple sclerosis (MS) through antigen presentation, cytokine secretion and repair processes.MethodsCombination of mass cytometry on blood cells from 60 MS patients at diagnosis and 29 healthy...

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Main Authors: Stéphane Rodriguez, Laura Couloume, Juliette Ferrant, Nicolas Vince, Marion Mandon, Rachel Jean, Celine Monvoisin, Simon Leonard, Simon Le Gallou, Nayane S. B. Silva, Sonia Bourguiba-Hachemi, David Laplaud, Alexandra Garcia, Romain Casey, Helene Zephir, Anne Kerbrat, Gilles Edan, Emmanuelle Lepage, Eric Thouvenot, Aurelie Ruet, Guillaume Mathey, Pierre-Antoine Gourraud, Karin Tarte, Celine Delaloy, Patricia Amé, Mikael Roussel, Laure Michel
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Immunology
Subjects:
multiple sclerosis
cerebrospinal fluid
classical monocyte
disability
antigen presentation
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1494842/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2024.1494842/full

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