Baseline Correction for HPLC Chromatograms by Using Free Open-Source Software

Baseline Correction for HPLC Chromatograms by Using Free Open-Source Software

Chromatograms with overlapping peaks and a baseline rise or upset constitute a great challenge for analysts. Such a case regarding the analysis of bupropion hydrochloride and its 5 impurities in a tablet formulation was used as a model. A baseline correction technique for liquid chromatography coupl...

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Bibliographic Details
Main Authors: Kostas Gkountanas, Ioanna Dagla, Evangelos Gikas, Anđelija Malenović, Yannis Dotsikas
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Analytica
Subjects:
data processing
peak integration
baseline correction
asymmetry least squares algorithm
experimental design
robustness testing
Online Access:https://www.mdpi.com/2673-4532/4/1/5

Internet

https://www.mdpi.com/2673-4532/4/1/5

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