Intestinal permeability and malabsorption of rifampin and isoniazid in active pulmonary tuberculosis

Intestinal permeability and malabsorption of rifampin and isoniazid in active pulmonary tuberculosis

Low antimycobacterial drug concentrations have been observed in tuberculosis (TB) patients under treatment. The lactulose/mannitol urinary excretion test (L/M), normally used to measure intestinal permeability, may be useful to assess drug absorption. The objective of this research was to study inte...

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Bibliographic Details
Main Authors: Valéria G. F. Pinheiro, Lysiane M. A. Ramos, Helena S. A. Monteiro, Elizabeth C. Barroso, Oluma Y. Bushen, Mônica C. Façanha, Charles A. Peloquin, Richard L. Guerrant, Aldo A. M. Lima
Format: Article
Language:English
Published: Elsevier
Series:Brazilian Journal of Infectious Diseases
Subjects:
Pulmonary tuberculosis
intestinal permeability
rifampin and isoniazid intestinal malabsorption
M. tuberculosis resistance
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702006000600003&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702006000600003&lng=en&tlng=en

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