Select Porcine Elongation Factor 1α Sequences Mediate Stable High-Level and Upregulated Expression of Heterologous Genes in Porcine Cells in Response to Primate Serum

Select Porcine Elongation Factor 1α Sequences Mediate Stable High-Level and Upregulated Expression of Heterologous Genes in Porcine Cells in Response to Primate Serum

Genetically engineered (GE) pigs with various combinations of genetic profiles have been developed using heterologous promoters. This study aimed to identify autologous promoters for high and ubiquitous expression of xenotransplantation relevant genes in GE pigs. A 1.4 kb upstream regulatory sequenc...

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Bibliographic Details
Main Authors: Wu-Sheng Sun, Hyeon Yang, Jin Gu No, Haesun Lee, Nahyun Lee, Minguk Lee, Man-Jong Kang, Keon Bong Oh
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Genes
Subjects:
promoter
porcine elongation factor 1α
expression
porcine cells
xenogeneic serum
Online Access:https://www.mdpi.com/2073-4425/12/7/1046

Internet

https://www.mdpi.com/2073-4425/12/7/1046

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