Increased iron in the substantia nigra pars compacta identifies patients with early Parkinson’s disease: A 3T and 7T MRI study

Increased iron in the substantia nigra pars compacta identifies patients with early Parkinson’s disease: A 3T and 7T MRI study

Degeneration in the substantia nigra (SN) pars compacta (SNc) underlies motor symptoms in Parkinson’s disease (PD). Currently, there are no neuroimaging biomarkers that are sufficiently sensitive, specific, reproducible, and accessible for routine diagnosis or staging of PD. Although iron is essenti...

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Bibliographic Details
Main Authors: Erind Alushaj, Nicholas Handfield-Jones, Alan Kuurstra, Anisa Morava, Ravi S. Menon, Adrian M. Owen, Manas Sharma, Ali R. Khan, Penny A. MacDonald
Format: Article
Language:English
Published: Elsevier 2024-01-01
Series:NeuroImage: Clinical
Subjects:
Parkinson’s disease
Neuroimaging
Quantitative susceptibility mapping
Iron
Midbrain
Online Access:http://www.sciencedirect.com/science/article/pii/S2213158224000160

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http://www.sciencedirect.com/science/article/pii/S2213158224000160

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