Zika Virus Infection Induces Elevation of Tissue Factor Production and Apoptosis on Human Umbilical Vein Endothelial Cells

Zika Virus Infection Induces Elevation of Tissue Factor Production and Apoptosis on Human Umbilical Vein Endothelial Cells

Zika virus (ZIKV) infection is typically characterized by a mild disease presenting with fever, maculopapular rash, headache, fatigue, myalgia, and arthralgia. A recent animal study found that ZIKV-infected pregnant Ifnar−/−mice developed vascular damage in the placenta and reduced amount of fetal c...

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Bibliographic Details
Main Authors: Fatih Anfasa, Marco Goeijenbier, Widagdo Widagdo, Jurre Y. Siegers, Noreen Mumtaz, Nisreen Okba, Debby van Riel, Barry Rockx, Marion P. G. Koopmans, Joost C. M. Meijers, Byron E. E. Martina
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-04-01
Series:Frontiers in Microbiology
Subjects:
Zika virus
endothelial cells
HUVECs
tissue factor
secondary hemostasis
apoptosis
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2019.00817/full

Internet

https://www.frontiersin.org/article/10.3389/fmicb.2019.00817/full

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