Administration of Denosumab Preserves Bone Mineral Density at the Knee in Persons With Subacute Spinal Cord Injury: Findings From a Randomized Clinical Trial

Administration of Denosumab Preserves Bone Mineral Density at the Knee in Persons With Subacute Spinal Cord Injury: Findings From a Randomized Clinical Trial

ABSTRACT Persons with neurologically motor‐complete spinal cord injury (SCI) have a marked loss of bone mineral density (BMD) of the long bones of the lower extremities, predisposing them to fragility fractures, especially at the knee. Denosumab, a commercially available human monoclonal IgG antibod...

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Bibliographic Details
Main Authors: Christopher M Cirnigliaro, Michael F La Fountaine, J Scott Parrott, Steven C Kirshblum, Cristin McKenna, Susan J Sauer, Sue A. Shapses, Lihong Hao, Isa A McClure, Joshua C Hobson, Ann M Spungen, William A Bauman
Format: Article
Language:English
Published: Oxford University Press 2020-08-01
Series:JBMR Plus
Subjects:
BONE MINERAL DENSITY
DENOSUMAB
DUAL ENERGY X‐RAY ABSORPTIOMETRY
IMMOBILIZATION OSTEOPOROSIS
PERIPHERAL QUANTITATIVE COMPUTED TOMOGRAPHY
SPINAL CORD INJURY
Online Access:https://doi.org/10.1002/jbm4.10375

Internet

https://doi.org/10.1002/jbm4.10375

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