Bimatoprost-loaded ocular inserts as sustained release drug delivery systems for glaucoma treatment: in vitro and in vivo evaluation.

Bimatoprost-loaded ocular inserts as sustained release drug delivery systems for glaucoma treatment: in vitro and in vivo evaluation.

The purpose of the present study was to develop and assess a novel sustained-release drug delivery system of Bimatoprost (BIM). Chitosan polymeric inserts were prepared using the solvent casting method and characterized by swelling studies, infrared spectroscopy, differential scanning calorimetry, d...

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Bibliographic Details
Main Authors: Juçara Ribeiro Franca, Giselle Foureaux, Leonardo Lima Fuscaldi, Tatiana Gomes Ribeiro, Lívia Bomfim Rodrigues, Renata Bravo, Rachel Oliveira Castilho, Maria Irene Yoshida, Valbert Nascimento Cardoso, Simone Odília Fernandes, Sebastião Cronemberger, Anderson José Ferreira, André Augusto Gomes Faraco
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4005758?pdf=render

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http://europepmc.org/articles/PMC4005758?pdf=render

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