The tumor suppressor 5A2, a synthetic miR-7-5p mimic, targets oncogenic and metabolic pathways, as revealed by transcriptome-wide analysis

The tumor suppressor 5A2, a synthetic miR-7-5p mimic, targets oncogenic and metabolic pathways, as revealed by transcriptome-wide analysis

As cancer is a multifactorial disease, the multimodal action of microRNAs makes them an attractive tool for novel therapeutic approaches. The tumor suppressive miR-7-5p has been shown to act on many aspects of oncogenesis, including cell proliferation, migration and angiogenesis, by targeting a spec...

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Bibliographic Details
Main Authors: Marion T. J. van den Bosch, Bryony J. Telford, Sanaz Yahyanejad, Thijs de Gunst, Harm C. den Boer, Rogier M. Vos, Chantal L. Duurland, Rianne Biemans, Ludwig J. Dubois, Laurens A. H. van Pinxteren, Roel Q. J. Schaapveld, Michel Janicot
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-07-01
Series:Frontiers in Drug Discovery
Subjects:
microRNA
RNA-sequencing
cancer metabolism
glycolysis
lipid nanoparticle
tumor suppressor
Online Access:https://www.frontiersin.org/articles/10.3389/fddsv.2023.1181637/full

Internet

https://www.frontiersin.org/articles/10.3389/fddsv.2023.1181637/full

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