MicroRNA-155 modulates Treg and Th17 cells differentiation and Th17 cell function by targeting SOCS1.

MicroRNA (miR)-155 is a critical player in both innate and adaptive immune responses. It can influence CD4(+) T cell lineage choice. To clarify the role of miR-155 in CD4(+) CD25(+) regulatory T (Treg)/T helper (Th)17 cell differentiation and function, as well as the mechanism involved, we performed...

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Bibliographic Details
Main Authors: Rui Yao, Yu-Lan Ma, Wei Liang, Huan-Huan Li, Zhi-Jun Ma, Xian Yu, Yu-Hua Liao
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3473054?pdf=render