A third SARS-CoV-2 spike vaccination improves neutralization of variants-of-concern

Abstract The emergence of SARS-CoV-2 variants that are more resistant to antibody-mediated neutralization pose a new hurdle in combating the COVID-19 pandemic. Although vaccines based on the original Wuhan sequence have been shown to be effective at preventing COVID-19, their efficacy is likely to b...

Full description

Bibliographic Details
Main Authors: Mitch Brinkkemper, Philip J. M. Brouwer, Pauline Maisonnasse, Marloes Grobben, Tom G. Caniels, Meliawati Poniman, Judith A. Burger, Ilja Bontjer, Melissa Oomen, Joey H. Bouhuijs, Cynthia A. van der Linden, Julien Villaudy, Yme U. van der Velden, Kwinten Sliepen, Marit J. van Gils, Roger Le Grand, Rogier W. Sanders
Format: Article
Language:English
Published: Nature Portfolio 2021-12-01
Series:npj Vaccines
Online Access:https://doi.org/10.1038/s41541-021-00411-7