Type I interferon signaling, cognition and neurodegeneration following COVID-19: update on a mechanistic pathogenetic model with implications for Alzheimer’s disease

Type I interferon signaling, cognition and neurodegeneration following COVID-19: update on a mechanistic pathogenetic model with implications for Alzheimer’s disease

COVID-19’s effects on the human brain reveal a multifactorial impact on cognition and the potential to inflict lasting neuronal damage. Type I interferon signaling, a pathway that represents our defense against pathogens, is primarily affected by COVID-19. Type I interferon signaling, however, is kn...

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Bibliographic Details
Main Authors: George D. Vavougios, Vasilis-Spyridon Tseriotis, Andreas Liampas, Theodore Mavridis, Gabriel A. de Erausquin, Georgios Hadjigeorgiou
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-03-01
Series:Frontiers in Human Neuroscience
Subjects:
Alzheimer’s disease
COVID-19
interferons
drug repositioning
innate immunity
neurogenesis
Online Access:https://www.frontiersin.org/articles/10.3389/fnhum.2024.1352118/full

Internet

https://www.frontiersin.org/articles/10.3389/fnhum.2024.1352118/full

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