Renal toxicity of methylprednisolone in male Wistar rats and the potential protective effect by boldine supplementation

Renal toxicity of methylprednisolone in male Wistar rats and the potential protective effect by boldine supplementation

Objective: Intravenous corticosteroids, methylprednisolone (MPL), which is one of the drugs that induce glomerular kidney diseases, when used for a long time at high dose by doctors to treat acute renal inflammation, promote the development of reactive oxygen species (ROS)-induced renal toxicity. Th...

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Bibliographic Details
Main Authors: Dalia Fouad, Esraa Shuker, Manal Farhood
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:Journal of King Saud University: Science
Subjects:
Methylprednisolone
Renal toxicity
Oxidative stress
DNA damage
Boldine
Anti-oxidant properties
Online Access:http://www.sciencedirect.com/science/article/pii/S1018364722005626

Internet

http://www.sciencedirect.com/science/article/pii/S1018364722005626

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