Immunostimulatory motifs enhance antiviral siRNAs targeting highly pathogenic avian influenza H5N1.

Highly pathogenic avian influenza (HPAI) H5N1 virus is endemic in many regions around the world and remains a significant pandemic threat. To date H5N1 has claimed almost 300 human lives worldwide, with a mortality rate of 60% and has caused the death or culling of hundreds of millions of poultry si...

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Bibliographic Details
Main Authors: Cameron R Stewart, Adam J Karpala, Sue Lowther, John W Lowenthal, Andrew G Bean
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3128588?pdf=render