Extracellular vesicles released by microglia and macrophages carry endocannabinoids which foster oligodendrocyte differentiation

Extracellular vesicles released by microglia and macrophages carry endocannabinoids which foster oligodendrocyte differentiation

IntroductionMicroglia and macrophages can influence the evolution of myelin lesions through the production of extracellular vesicles (EVs). While microglial EVs promote in vitro differentiation of oligodendrocyte precursor cells (OPCs), whether EVs derived from macrophages aid or limit OPC maturatio...

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Bibliographic Details
Main Authors: Marta Lombardi, Federica Scaroni, Martina Gabrielli, Stefano Raffaele, Elisabetta Bonfanti, Fabia Filipello, Paola Giussani, Silvia Picciolini, Nicole Kerlero de Rosbo, Antonio Uccelli, Maria Teresa Golia, Giulia D’Arrigo, Tiziana Rubino, Kourosh Hooshmand, Cristina Legido-Quigley, Chiara Fenoglio, Alice Gualerzi, Marta Fumagalli, Claudia Verderio
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-02-01
Series:Frontiers in Immunology
Subjects:
macrophages
microglia
extracellular vesicles
oligodendrocytes
endocannabinoids
anandamide
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1331210/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2024.1331210/full

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