Design and Synthesis of Thionated Levofloxacin: Insights into a New Generation of Quinolones with Potential Therapeutic and Analytical Applications

Design and Synthesis of Thionated Levofloxacin: Insights into a New Generation of Quinolones with Potential Therapeutic and Analytical Applications

Levofloxacin is a widely used fluoroquinolone in several infectious diseases. The structure–activity relationship of levofloxacin has been studied. However, the effect of changing the carbonyl into thiocarbonyl of levofloxacin has not been investigated up to the date of this report. In this work, le...

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Bibliographic Details
Main Authors: Ali I. M. Ibrahim, Hassan Abul-Futouh, Laurance M. S. Bourghli, Mohammad Abu-Sini, Suhair Sunoqrot, Balqis Ikhmais, Vibhu Jha, Qusai Sarayrah, Dina H. Abulebdah, Worood H. Ismail
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Current Issues in Molecular Biology
Subjects:
thionated levofloxacin
antibacterial
molecular docking
anticancer
electronic excitation
Online Access:https://www.mdpi.com/1467-3045/44/10/316

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https://www.mdpi.com/1467-3045/44/10/316

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