Extracellular matrix stiffness mediates radiosensitivity in a 3D nasopharyngeal carcinoma model

Extracellular matrix stiffness mediates radiosensitivity in a 3D nasopharyngeal carcinoma model

Abstract Purpose Radiotherapy is one of the essential treatment modalities for nasopharyngeal carcinoma (NPC), however, radioresistance still poses challenges. Three-dimensional (3D) tumor culture models mimic the in vivo growth conditions of cells more accurately than 2D models. This study is to co...

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Bibliographic Details
Main Authors: Yanhua Fang, Shanshan Liang, Jianong Gao, Zhe Wang, Cheng Li, Ruoyu Wang, Weiting Yu
Format: Article
Language:English
Published: BMC 2022-11-01
Series:Cancer Cell International
Subjects:
Nasopharyngeal carcinoma
Radioresistance
Extracellular matrix
Stiffness
3D culture model
Online Access:https://doi.org/10.1186/s12935-022-02787-5

Internet

https://doi.org/10.1186/s12935-022-02787-5

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