A Rab6 to Rab11 transition is required for dense-core granule and exosome biogenesis in Drosophila secondary cells.

A Rab6 to Rab11 transition is required for dense-core granule and exosome biogenesis in Drosophila secondary cells.

Secretory cells in glands and the nervous system frequently package and store proteins destined for regulated secretion in dense-core granules (DCGs), which disperse when released from the cell surface. Despite the relevance of this dynamic process to diseases such as diabetes and human neurodegener...

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Bibliographic Details
Main Authors: Adam Wells, Cláudia C Mendes, Felix Castellanos, Phoebe Mountain, Tia Wright, S Mark Wainwright, M Irina Stefana, Adrian L Harris, Deborah C I Goberdhan, Clive Wilson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-10-01
Series:PLoS Genetics
Online Access:https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1010979&type=printable

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https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1010979&type=printable

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