The solution surface of the Li-Stephens haplotype copying model
Abstract The Li-Stephens (LS) haplotype copying model forms the basis of a number of important statistical inference procedures in genetics. LS is a probabilistic generative model which supposes that a sampled chromosome is an imperfect mosaic of other chromosomes found in a population. In the frequ...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
BMC
2023-08-01
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Series: | Algorithms for Molecular Biology |
Subjects: | |
Online Access: | https://doi.org/10.1186/s13015-023-00237-z |