Exploring the role of macrophages in the progression from atypical hyperplasia to endometrial carcinoma through single-cell transcriptomics and bulk transcriptomics analysis

IntroductionIn this study, we aimed to identify key genes in endometrial cancer by conducting single-cell analysis of macrophages.MethodsWe sourced clinical data from the TCGA database as well as supplementary datasets GSE201926 and GSE173682. Using bulk-seq data of atypical endometrial hyperplasia...

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Bibliographic Details
Main Authors: Xiaolei Song, Re Na, Nianghai Peng, Wenming Cao, Yan Ke
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-09-01
Series:Frontiers in Endocrinology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2023.1198944/full